This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Fusion protein of human AOAH
Swissprot
P28039
Synonyms
Acyloxyacyl hydrolase (neutrophil)Acyloxyacyl hydrolase large subunitAOAHAOAH