BGLAP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76730A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using BGLAP Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human brain using BGLAP Polyclonal Antibody at dilution of 1:40
Product Name
BGLAP Polyclonal Antibody
Catalog Number
RD76730A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner.
Immunogen Information
Immunogen
Synthetic peptide of human BGLAP
Swissprot
P02818
Synonyms
BGLAPBGPBone gamma carboxyglutamate (gla) proteinBone gamma carboxyglutamate gla protein osteocalcinBone gamma carboxyglutamate proteinBone Gla proteinGamma carboxyglutamic acid containing proteinGamma-carboxyglutamic acid-containing proteinOCOCN
Gene Accession
NP_954642
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas