For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD217879A
Western blot analysis of HEPG2 HUVEC and NIH/3T3 cell Human heart tissue Mouse heart tissue PC-3 cell lysates using COX6C Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using COX6C Polyclonal Antibody at dilution of 1:25(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using COX6C Polyclonal Antibody at dilution of 1:25(×200)
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
Immunogen Information
Immunogen
Synthetic peptide of human COX6C
Swissprot
P09669
Synonyms
COX 6CCox6cCOX6CCytochrome c oxidase polypeptide VIcCytochrome c oxidase subunit 6Ccytochrome c oxidase subunit VIcCytochrome c oxidase subunit VIc preprotein