Cytokeratin 8 (CK8) is a high molecular weight B-type cytokeratin, which mainly marks non squamous epithelium. Therefore, it is mainly used for the diagnosis of adenocarcinoma and ductal carcinoma. Squamous carcinoma generally does not express CK8. It has been reported that hepatocellular carcinoma mainly expresses CK8 and CK18. Cytokeratin 18 (CK18), with a molecular weight of 45kda, belongs to low molecular weight type a cytokeratin. It mainly marks all kinds of monolayer epithelium, including glandular epithelium, while stratified squamous epithelium is often negative. It is mainly used for the diagnosis of adenocarcinoma.
Immunogen Information
Swissprot
P05787,P05783
Synonyms
CK 8CK-8CK18CK8CYK18CYK8Cytokeratin 18Cytokeratin 8Cytokeratin-8K18K2C8K2C8_HUMANK8Keratin 18Keratin 8KeratinKeratin type I cytoskeletal 18keratin type II cytoskeletal 8Keratin-8KRT18KRT8type II cytoskeletal 8Type-II keratin Kb8
Applications
Reactivity
Human
Tested Applications
IHC-P
Conjugation
Unconjugated
Storage Instructions
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.
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