DAAM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76801A
Western Blot analysis of Human testis tissue using DAAM1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human cervical cancer using DAAM1 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human brain using DAAM1 Polyclonal Antibody at dilution of 1:50
Product Name
DAAM1 Polyclonal Antibody
Catalog Number
RD76801A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex.
Immunogen Information
Immunogen
Synthetic peptide of human DAAM1
Swissprot
Q9Y4D1
Synonyms
DAAM 1Dishevelled associated activator of morphogenesis 1FLJ41657KIAA0666
Calculated MW
123 kDa
Gene Accession
NP_001257449
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas