DKK2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75147A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DKK2 Polyclonal Antibody at dilution 1:60
Product Name
DKK2 Polyclonal Antibody
Catalog Number
RD75147A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Immunogen Information
Immunogen
Recombinant protein of human DKK2
Swissprot
Q9UBU2
Synonyms
Dickkopf 2Dickkopf gene 2Dickkopf homolog 2Dickkopf related protein 2Dickkopf WNT signaling pathway inhibitor 2Dickkopf-2Dickkopf-related protein 2Dickkopf2DKK 2Dkk-2Dkk2DKK2hDkk 2hDkk-2hDkk2
Gene Accession
BC126328
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas