EIF4E Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82570A
Immunohistochemistry of paraffin-embedded Human lung cancer using EIF4E Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using EIF4E Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using EIF4E Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
EIF4E Polyclonal Antibody
Catalog Number
RD82570A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
A synthetic peptide of human EIF4E (NP_001959.1).
Gene ID
1977
Swissprot
P06730
Synonyms
AUTS19CBPEIF4E1EIF4EL1EIF4FeIF-4EEIF4E
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas