Members of the F-box protein family, such as FBXO45, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (summary by Jin et al., 2004 [PubMed 15520277]).
Immunogen Information
Immunogen
Synthetic peptide of human FBXO45
Swissprot
P0C2W1
Synonyms
F box protein 45F-box only protein 45F-box/SPRY domain-containing protein 1FBSP1FBX45fbxo45hFbxo45