Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
Immunogen Information
Immunogen
Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253.
Swissprot
O43524
Synonyms
AF6q21AF6q21 proteinDKFZp781A0677FKHR2FKHRL 1FKHRL1FKHRL1P2Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1Forkhead box O3Forkhead box O3AForkhead box protein O3Forkhead box protein O3AForkhead Drosophila homolog of in rhabdomyosarcoma
Calculated MW
71 kDa
Observed MW
97 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4