This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
Immunogen Information
Immunogen
Synthetic peptide of human HOXD9
Swissprot
P28356
Synonyms
homeobox D9Homeobox protein Hox D9Homeobox protein Hox-4CHomeobox protein Hox-5.2Homeobox protein Hox-D9Hox 4.3Hox 5.2HOX4HOX4CHOXD9HXD9RP23 313J15.10