Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Immunogen Information
Immunogen
Fusion protein of human L3MBTL2
Swissprot
Q969R5
Synonyms
3bt like 2 protein3bt like proteinDKFZP761I141H-l(3)mbt-like protein 2H-l(3)mbt-like proteinHlHl(3)mbt like proteinHl(3)mbtlLl(3)mbt like 2 (Drosophila)l(3)mbt like 2L(3)mbt-like 2 proteinL(3)mbt-like protein 2L3MBTL2LethalLethal(3)mal