LMNB1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218237A
Western blot analysis of Hela cells HT29 cells human fetal liver tissue Human testis tissue 231 cells K562 cells human bladder transitional cell carcinoma tissue using LMNB1 Polyclonal Antibody at dilution of 1:750
Immunohistochemistry of paraffin-embedded Human tonsil tissue using LMNB1 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LMNB1 Polyclonal Antibody at dilution of 1:60(×200)
Product Name
LMNB1 Polyclonal Antibody
Catalog Number
RD218237A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Immunogen Information
Immunogen
Fusion protein of human LMNB1
Swissprot
P20700
Synonyms
ADLDlamin B1Lamin-B1LMNLMN2LMNBLmnb1LMNB1MGC111419OTTHUMP00000159218
Calculated MW
67 kDa
Observed MW
Refer to figures
Gene Accession
BC012295
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas