MDFI Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218801A
Western blot analysis of Human placenta tissue lysate using MDFI Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MDFI Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MDFI Polyclonal Antibody at dilution of 1:55(×200)
Product Name
MDFI Polyclonal Antibody
Catalog Number
RD218801A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.
Immunogen Information
Immunogen
Fusion protein of human MDFI
Swissprot
Q99750
Synonyms
I MFI mfaInhibitor of MyoD family aMdfiMDFIMyoD family inhibitorMyogenic repressor I-mfOTTHUMP00000016375OTTHUMP00000016376OTTHUMP00000196103OTTHUMP00000196414OTTHUMP00000196415
Calculated MW
25 kDa
Observed MW
Refer to figures
Gene Accession
BC007836
Applications
Reactivity
Human, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas