The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P23284
Synonyms
AA408962AA553318AI844835Cphn 2Cphn2Cyclophilin BCyclophilin like proteinCyP 20bCYP S1CYP-S1CYPBEC 5.2.1.8MGC14109MGC2224OI9peptidyl prolyl cis trans isomerase BPeptidyl prolyl cis trans isomerase B precursorPeptidyl-prolyl cis-trans isome
Observed MW
21 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF
Conjugation
Unconjugated
Dilution
WB 1:1000-2000, IHC 1:50-300, IF 1:50-300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4