PTEN Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219312A
Western blot analysis of NIH/3T3 cell lysate using PTEN Polyclonal Antibody at dilution of 1:1100
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PTEN Polyclonal Antibody at dilution of 1:25(×200)
Product Name
PTEN Polyclonal Antibody
Catalog Number
RD219312A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
PTEN (also designated MMAC1),products of tumor suppressor genes,are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors,such as brain,breast,kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the Signal transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol.
Immunogen Information
Immunogen
Synthetic peptide of human PTEN
Swissprot
P60484
Synonyms
10q23delBZSDECGLM2MGC11227MHAMMMAC1MMAC1 phosphatase and tensin homolog deleted on chromosome 10Mutated in multiple advanced cancers 1Phosphatase and tensin homologPhosphatase and tensin like proteinPhosphatidylinositol 345-trisphosphate 3-ph
Calculated MW
47 kDa
Observed MW
Refer to figures
Gene Accession
NP000305
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.