Recombinant IMPDH2 Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87045A
Western blot detection of IMPDH2 in Hela,A549,HL-60,U2OS,C6 using IMPDH2 Rabbit mAb(1:1000 diluted)
Immunohistochemistry of IMPDH2 in paraffin-embedded Human breast cancer tissue using IMPDH2 Rabbit mAb at dilution 1:50
Product Name
Recombinant IMPDH2 Monoclonal Antibody
Catalog Number
RD87045A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Immunogen Information
Immunogen
A synthetic peptide of human IMPDH2
Gene ID
3615
Swissprot
P12268
Synonyms
IMDH2IMP (inosine monophosphate) dehydrogenase 2IMP dehydrogenase 2IMP oxireductase 2IMPD 2IMPD2IMPDH 2IMPDH IIIMPDH-IIImpdh2Inosine 5' monophosphate dehydrogenase 2Inosine 5' phosphate dehydrogenase 2Inosine monophosphate dehydrogenase type I
Calculated MW
115kDa
Observed MW
150kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas