Recombinant Lactate Dehydrogenase A Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86924A
Western blot detection of LDHA in Jurkat,Rat Brain,C6,Hela cell lysates using LDHA Rabbit mAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.
Product Name
Recombinant Lactate Dehydrogenase A Monoclonal Antibody
Catalog Number
RD86924A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Immunogen Information
Immunogen
A synthetic peptide of human Lactate Dehydrogenase
Gene ID
3939
Swissprot
P00338
Synonyms
Cell proliferation-inducing gene 19 proteinGSD11L lactate dehydrogenase A chainl7R2LDH MLDH muscle subunitLDH1PIG19 Proliferation-inducing gene 19
Calculated MW
59kDa
Observed MW
59kDa
Applications
Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas