Recombinant STAT5b Monoclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86986A
Western blot detection of STAT5b in Hela,A549,HL-60 using STAT5b Rabbit mAb(1:1000 diluted)
Immunohistochemistry of STAT5b in paraffin-embedded Human breast cancer tissue using STAT5b Rabbit mAb at dilution 1:50
Product Name
Recombinant STAT5b Monoclonal Antibody
Catalog Number
RD86986A
Clonality
Monoclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands,such as IL2,IL4,CSF1,and different growth hormones. It has been shown to be involved in diverse biological processes,such as TCR signaling,apoptosis,adult mammary gland development,and sexual dimorphism of liver gene expression.
Immunogen Information
Immunogen
Recombinant protein of human STAT5b
Gene ID
6777
Swissprot
P51692
Synonyms
STAT5STAT5B
Calculated MW
18kDa
Observed MW
18kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-P
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:50-1:100
Concentration
300 μg/mL
Storage Buffer
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.