SARS-CoV-2 E Protein Polyclonal Antibody(2019-nCoV)
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90432A
Product Name
SARS-CoV-2 E Protein Polyclonal Antibody(2019-nCoV)
Catalog Number
RD90432A
Clonality
Polyclonal
Purification Method
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 E protein
Isotype
IgG
Host
Rabbit
Background
Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Immunogen Information
Immunogen
Recombinant SARS-CoV-2 E protein
Synonyms
2019-nCoV E protein2019-nCoV sM proteinEnvelope small membrane protein
Applications
Reactivity
SARS-COV2
Tested Applications
ELISA
Conjugation
Unconjugated
Dilution
ELISA 1:4000-1:8000
Concentration
0.30mg/mL
Storage Buffer
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.