Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Immunogen Information
Immunogen
Recombinant fusion protein of human TNFAIP8
Gene ID
25816
Swissprot
O95379
Synonyms
TNFAIP8GG2-1MDC-3.13NDEDSCC-S2SCCS2
Calculated MW
93kDa
Observed MW
102kDa
Applications
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.