AF/LE Purified Anti-Human CD11a Antibody

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Catalog NumberRD22231F

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Product NameAF/LE Purified Anti-Human CD11a Antibody
Catalog NumberRD22231F
IsotypeMouse IgG1, κ
Clone NumberR7-1

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Immunogen Information
Gene ID3683
SynonymsIntegrin alpha-LLFA-1ACD11AITGAL
Tested applicationsFCM,FA
ConjugationNone (Purified antibody-Azide Free/Low endotoxin)
Dilution0.5 mg/mL
Storage Buffer0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage InstructionsStore at 2~8°C. Do not freeze.
Research Area

Cancer, Immunology, Signal transduction, Stem cells

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