| Product Name | AF/LE Purified Anti-Human CD11a Antibody |
|---|---|
| Catalog Number | RD22231F |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Clone Number | R7-1 |
AF/LE Purified Anti-Human CD11a Antibody
| Catalog Number | RD22231F |
|---|
For more information on our kits, please contact us at [email protected]
Overview
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Immunogen Information
| Gene ID | 3683 |
|---|---|
| Swissprot | P20701 |
| Synonyms | Integrin alpha-LLFA-1ACD11AITGAL |
Applications
| Reactivity | Human |
|---|---|
| Tested applications | FCM,FA |
| Conjugation | None (Purified antibody-Azide Free/Low endotoxin) |
| Dilution | 0.5 mg/mL |
| Storage Buffer | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Storage Instructions | Store at 2~8°C. Do not freeze. |
Research Area
Cancer, Immunology, Signal transduction, Stem cells
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