(KO Validated) ADRBK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82268A
Western blot analysis of extracts from normal (control) and ADRBK1 knockout (KO) 293T cells using ADRBK1 Polyclonal Antibody at dilution of 1:500.
Western blot analysis of extracts of various cell lines using ADRBK1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat brain using ADRBK1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human esophageal cancer using ADRBK1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using ADRBK1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Variation
Quantity
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Overview
Product Name
(KO Validated) ADRBK1 Polyclonal Antibody
Catalog Number
RD82268A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Immunogen Information
Immunogen
Recombinant fusion protein of human ADRBK1 (NP_001610.2).
Gene ID
156
Swissprot
P25098
Synonyms
GRK2ADRBK1BARK1BETA-ARK1
Calculated MW
79 kDa
Observed MW
80 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas