(KO Validated) HuR / ELAVL1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82230A
Western blot analysis of extracts of various cell lines using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts from normal (control) and HuR / ELAVL1 knockout (KO) 293T cells using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse kidney using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Rat testis using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human kidney cancer using HuR / ELAVL1 Polyclonal Antibody at dilution of 1:200 (40x lens).
Immunofluorescence analysis of MCF-7 cells using HuR / ELAVL1 Polyclonal Antibody
Product Name
(KO Validated) HuR / ELAVL1 Polyclonal Antibody
Catalog Number
RD82230A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Immunogen Information
Immunogen
Recombinant fusion protein of human HuR / ELAVL1 (NP_001410.2).
Gene ID
1994
Swissprot
Q15717
Synonyms
ELAV1HURHuaMelGHuR / ELAVL1ELAVL1
Calculated MW
36 kDa/38 kDa
Observed MW
37 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:100-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas