(KO Validated) IGF1R Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86735A
Western blot analysis of extracts from normal (control) and IGF1R knockout (KO) 293T cells using IGF1R Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using IGF1R Polyclonal Antibody at 1:3000 dilution.
Product Name
(KO Validated) IGF1R Polyclonal Antibody
Catalog Number
RD86735A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human IGF1R
Gene ID
3480
Swissprot
P08069
Synonyms
IGF1RCD221IGFIRIGFRJTK13
Calculated MW
21kDa/54kDa/57kDa
Observed MW
57KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas