(KO Validated) SIRT5 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89703A
Western blot analysis of extracts from normal (control) and SIRT5 knockout (KO) 293T cells, using SIRT5 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using SIRT5 Polyclonal Antibody at 1:1000 dilution.
Product Name
(KO Validated) SIRT5 Polyclonal Antibody
Catalog Number
RD89703A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human SIRT5
Gene ID
23408
Swissprot
Q9NXA8
Synonyms
SIRT5SIR2L5sirtuin 5
Calculated MW
57kDa/61kDa/70kDa
Observed MW
80KDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.