The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Immunogen Information
Immunogen
Recombinant fusion protein of human AASDHPPT
Gene ID
60496
Swissprot
Q9NRN7
Synonyms
AASDHPPTAASD-PPTACPSCGI-80LYS2LYS5
Calculated MW
23-27kDa/58kDa/119-133kDa/365- 369kDa
Observed MW
52kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.