The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
Immunogen Information
Immunogen
Synthetic peptide of human AATF
Swissprot
Q9NY61
Synonyms
AATFAATFApoptosis antagonizing transcription factorApoptosis-antagonizing transcription factorBFR2CHE 1CHE1DEDProtein AATFRb binding protein Che 1Rb-binding protein Che-1
Calculated MW
63 kDa
Gene Accession
NP_036270
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4