The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Immunogen Information
Immunogen
Recombinant protein of human ABCB8
Swissprot
Q9NUT2
Synonyms
ATP binding cassette sub family B member 8ABCB8ABCB8ATP binding cassette sub family B (MDR/TAP) member 8ATP binding cassette sub family B member 8 mitochondrialATP-binding cassette sub-family B member 8EST328128M ABC1M-ABC1MABC1Mitochondrial ABC
Calculated MW
80 kDa
Gene Accession
BC141836
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4