ABHD12 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD88904A
Western blot analysis of extracts of various cell lines using ABHD12 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using ABHD12 Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
ABHD12 Polyclonal Antibody
Catalog Number
RD88904A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human ABHD12
Gene ID
26090
Swissprot
Q8N2K0
Synonyms
ABHD12ABEM46L2C20orf22PHARCdJ965G21.2ABHD12
Observed MW
Refer to figures

Applications

Circle
Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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