ABHD2 encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein.ABHD2 (Abhydrolase Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include carboxylic ester hydrolase activity. An important paralog of this gene is ABHD3.
Immunogen Information
Immunogen
Synthetic peptide of human ABHD2
Swissprot
P08910
Synonyms
2210009N18Rikabhydrolase domain containing 2Abhydrolase domain-containing protein 2alpha/beta hydrolase domain containing protein 2HS1 2Labh 2LABH2Lung alpha/beta hydrolase 2MGC107122MGC111112MGC26249PHPS1 2protein PHPS1-2
Gene Accession
NP008942
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.5 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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