ABI2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252174A
Western blot analysis of K562 cell Mouse heart tissue Jurkat cell lysates using ABI2 Polyclonal Antibody at dilution of 1:550
Product Name
ABI2 Polyclonal Antibody
Catalog Number
RD252174A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
Immunogen Information
Immunogen
Fusion protein of human ABI2
Swissprot
Q9NYB9
Synonyms
Abelson interactor 2ABI 2Abi-2ABI2ABI2ABI2BAbl binding protein 3Abl interacting protein 1 (SH3 containing protein)Abl interactor 2Abl interactor protein 2bAbl-binding protein 3AblBP3AIP 1Arg binding protein 1Arg protein tyrosine kinase bindi
Calculated MW
56 kDa
Observed MW
Refer to figures
Gene Accession
BC001439
Applications
Reactivity
Human, Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas