A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.
Immunogen Information
Immunogen
Recombinant protein of human ABI3BP
Swissprot
Q7Z7G0
Synonyms
ABI gene family member 3 (NESH) binding proteinABI gene family member 3 binding proteinABI gene family member 3-binding proteinABI3BPFLJ41743FLJ41754Nesh binding proteinNesh BPNesh-binding proteinNeshBPTarget of Nesh SH3Target of Nesh-SH3Tarsh
Gene Accession
BC030221
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4