This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human ABO
Swissprot
P16442
Synonyms
A transferaseA3GALNTA3GALT1ABO A3 transferaseAboABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase)ABO glycosyltransferaseABO weak transferB (A) alpha 13 glactosyltransferaseB
Gene Accession
NP_065202
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4