This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Immunogen Information
Immunogen
Synthetic peptide of human ACD
Swissprot
Q96AP0
Synonyms
AcdACDAdrenocortical dysplasia homologAdrenocortical dysplasia protein homologPIP1POT1 and TIN2 organizing proteinPOT1 and TIN2-interacting proteinTIN2 interacting protein 1TINT1TPP1