The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ACE2
Swissprot
Q9BYF1,Q8R0I0,Q5EGZ1
Synonyms
ACE 2ACE related carboxypeptidaseACE-related carboxypeptidaseACE2ACE2ACEHAngiotensin converting enzyme 2Angiotensin converting enzyme homologAngiotensin converting enzyme like proteinAngiotensin I Converting Enzyme (peptidyl dipeptidase A) 2Angi
Calculated MW
92 kDa
Observed MW
95 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
330 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4