ACMSD Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75418A
Western Blot analysis of Raji cell using ACMSD Polyclonal Antibody at dilution of 1:400
Variation
Quantity
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Overview
Product Name
ACMSD Polyclonal Antibody
Catalog Number
RD75418A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Immunogen Information
Immunogen
Recombinant protein of human ACMSD
Swissprot
Q8TDX5
Synonyms
2 amino 3 carboxymuconate 6 semialdehyde decarboxylase2-amino-3-carboxymuconate-6-semialdehyde decarboxylaseacmsdACMSDAminocarboxymuconate semialdehyde decarboxylasePicolinate carboxylase
Calculated MW
38 kDa
Gene Accession
BC016018
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas