This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.
Immunogen Information
Immunogen
Synthetic peptide of human ADAM12
Swissprot
O43184
Synonyms
A disintegrin and metalloproteinase domain 12ADA12ADAM 12ADAM metallopeptidase domain 12ADAM12CAR10Disintegrin and metalloproteinase domain-containing protein 12MCMPMCMPMltnaMeltrin alphaMeltrin-alphaMetalloprotease disintegrin 12 transmembrane
Gene Accession
NP_003465
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4