This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Immunogen Information
Immunogen
Recombinant protein of human ADAMTS18
Swissprot
Q8TE60
Synonyms
A disintegrin and metalloproteinase with thrombospondin motifs 18A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21ADA
Gene Accession
BC063283
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4