This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human ADCY4
Swissprot
Q8NFM4
Synonyms
AC4Adcy4ADCY4Adenylate cyclase 4Adenylate cyclase type 4Adenylate cyclase type IVAdenylyl cyclase 4Adenylyl cyclaseATP pyrophosphate lyase 4ATP pyrophosphate lyaseATP pyrophosphate-lyase 4
Gene Accession
BC117473
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4