ADRM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218828A
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ADRM1 Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ADRM1 Polyclonal Antibody at dilution of 1:70(×200)
Product Name
ADRM1 Polyclonal Antibody
Catalog Number
RD218828A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
Immunogen Information
Immunogen
Fusion protein of human ADRM1
Swissprot
Q16186
Synonyms
110 kDa cell membrane glycoproteinadhesion regulating molecule 1Adhesion-regulating molecule 1ADRM 1Adrm1ADRM1ARM 1ARM-1ARM1Gp110hRpn13M(r) 110000 surface antigenProteasomal ubiquitin receptor ADRM1proteasome regulatory particle non ATPase 1
Gene Accession
BC017245
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
1.26 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas