AF/LE Purified Anti-Human CD11a Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AF/LE Purified Anti-Human CD11a Antibody
Catalog Number
RD22231F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Immunogen Information
Gene ID
3683
Swissprot
P20701
Synonyms
Integrin alpha-LLFA-1ACD11AITGAL
Applications
Reactivity
Human
Tested Applications
FCM,FA
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Concentration
0.5 mg/mL
Storage Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Instructions
Store at 2~8°C. Do not freeze.
Research Areas