AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody
Catalog Number
RD21390F
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Background
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Immunogen Information
Gene ID
12766
Swissprot
O88410
Synonyms
C-X-C chemokine receptor type 3Cxcr3CXC-R3CXCR-3Interferon-inducible protein 10 receptorIP-10 receptorCD183/CXCR3
Applications
Reactivity
Mouse
Tested Applications
FCM,Block
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Concentration
0.5 mg/mL
Storage Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Instructions
Store at 2~8°C. Do not freeze.
Research Areas