AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD22112F
Product Name
AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody
Catalog Number
RD22112F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Immunogen Information
Gene ID
84868
Swissprot
Q8VIM0
Synonyms
TIM3TIMD3HAVcr-2TIMD-3
Applications
Reactivity
Mouse
Tested Applications
FCM,Block
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Concentration
0.5 mg/mL
Storage Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Instructions
Store at 2~8°C. Do not freeze.
Research Areas