AF/LE Purified Anti-Mouse CD40 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AF/LE Purified Anti-Mouse CD40 Antibody
Catalog Number
RD20437F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Immunogen Information
Gene ID
21939
Swissprot
P27512
Synonyms
Tumor necrosis factor receptor superfamily member 5Cd40B-cell surface antigen CD40Bp50CD40L receptorCD40Tnfrsf5
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
None (Purified antibody-Azide Free/Low endotoxin)
Concentration
0.5 mg/mL
Storage Buffer
0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage Instructions
Store at 2~8°C. Do not freeze.
Research Areas