Human peripheral blood lymphocytes are stained with Anti-Human CD11a Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
Immunogen Information
Gene ID
3683
Swissprot
P20701
Synonyms
Integrin alpha-LItgalCD11 antigen-like family member ALFA-1ALymphocyte antigen 15Ly-15CD11a
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.