Human peripheral blood monocytes are stained with Anti-Human CD11c Monoclonal Antibody(AF488 Conjugated)(filled gray histogram). Unstained monocytes (empty black histogram) are used as control.
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Overview
Product Name
AF488 Anti-Human CD11c Antibody
Catalog Number
RD21459F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Immunogen Information
Gene ID
3687
Swissprot
P20702
Synonyms
Integrin alpha-XItgaxCD11 antigen-like family member CLeukocyte adhesion receptor p150+95CD11c