AF488 Anti-Human CD123 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21449F
Human peripheral blood lymphocytes are stained with Anti-Human CD123 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Human CD123 Antibody
Catalog Number
RD21449F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Immunogen Information
Gene ID
3563
Swissprot
P26951
Synonyms
IL-3RαIL-3 Receptor alpha
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas