Human peripheral blood lymphocytes are stained with APC Anti-Human CD19 Antibody and AF 488 Anti-Human CD3 Antibody (Left). Lymphocytes are stained with APC Anti-Human CD19 Antibody and AF 488 Mouse IgG1, κ Isotype Control (Right).
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.