AF488 Anti-Human CD35 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20803F
Human peripheral blood lymphocytes are stained with Anti-Human CD35 Monoclonal Antibody(AF488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Human CD35 Antibody
Catalog Number
RD20803F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.
Immunogen Information
Gene ID
1378
Swissprot
P17927
Synonyms
Complement receptor type 1CR1C3b/C4b receptorCD35CR1C3BR
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas