Human peripheral blood lymphocytes are stained with Anti-Human CD41 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
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Overview
Product Name
AF488 Anti-Human CD41 Antibody
Catalog Number
RD20995F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.